Africa faces urgent health challenges from infectious diseases to rising non-communicable conditions yet only 1% of global research focuses on the continent. Despite bearing 25% of the global disease burden, Africa’s representation in research remains critically low, perpetuating reliance on external solutions. By equipping local medical professionals with skills, mentorship, and collaboration platforms, we empower them to drive context-specific innovations, strengthen health systems, and redefine global priorities. Visit the WHO Global Observatory on Health R&D for more.